منابع مشابه
Local bone erosions in rheumatoid arthritis
Bone erosion is a hallmark of rheumatoid arthritis. Recent evidence from experimental arthritis suggests that osteoclasts are essential for the formation of local bone erosions. Two essential regulators of osteoclastogenesis have recently been described: the receptor-activator of nuclear factor kappa B ligand, which promotes osteoclast maturation, and osteoprotegerin (OPG), which blocks osteocl...
متن کاملDenosumab, cortical bone and bone erosions in rheumatoid arthritis.
Takeuchi et al demonstrate an additional inhibitory effect on the progression of bone erosions in rheumatoid arthritis (RA) with the addition to methotrexate of an anti-receptor activator of nuclear factor kappa-B ligand (RANKL) antibody, denosumab, confirming results already reported 8 years ago by Cohen and colleagues. Insufficient inhibition of structural joint damage by diseasemodifying ant...
متن کاملRelation between bone erosions and rheumatoid factor isotypes.
Total rheumatoid factor (RF) activity and individual RF isotypes were measured in 62 patients with rheumatic diseases. Retrospective analysis of available x rays showed an association between IgA RF and the occurrence of periarticular bone erosions in hands. In contrast, IgG RF and IgM RF did not show any significant association with erosions. Furthermore, a close correlation was observed betwe...
متن کاملPICTORIAL ESSAY Ultrasonography in the evaluation of bone erosions
Objective—To demonstrate the diagnostic eYcacy of ultrasonography in depicting erosions in patients with rheumatoid arthritis and to compare sonographic and radiographic findings. Methods—Sonographic images were obtained with an AU-4 Idea Esaote Biomedica (Genoa, Italy) equipped with a 13 MHz linear transducer. Results—The images reported in this essay are representative examples of the ability...
متن کاملJoint scintigraphy and erosions.
Correspondence Joint scintigraphy and erosions SIR, Isotope studies have been widely used in rheumatol-ogy for about 20 years. The study by Desaulniers and coworkers indicated that skeletal scintigraphy was a more sensitive method for the detection of inflammatory joint disease than radiography.' It appeared to be more sensitive than clinical evaluation in the diagnosis of joint inflammation of...
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ژورنال
عنوان ژورنال: Reumatismo
سال: 2011
ISSN: 2240-2683,0048-7449
DOI: 10.4081/reumatismo.2003.52